Adenine nucleotide binding and photoincorporation in Glanzmann's thrombasthenia platelets
نویسندگان
چکیده
منابع مشابه
Conformationally restricted adenine nucleotide analogs in mitochondrial adenine nucleotide transport.
The conformationally restricted adenine nucleotide analogs 8,3'anhydro-8-oxy-9-(beta-D-xylofuranosyl)adenine-5'-O-tri(di)-phosphate (I), and 8,2'-anhydro-8-oxy-9-(beta-D-arabinofuranosyl) adenine-5'-O-tri(di)-phosphate (II), were prepared chemically as their alpha-32P-labelled compounds and compared with syn-structured 8-bromo AT(D)P in mitochondrial adenine nucleotide translocation. The experi...
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Increased activity of blood platelets contributes to vascular complications in patients with diabetes. The aim of this work was to investigate whether persisting hyperglycemia in diabetic patients generates excessive accumulation of ATP/ADP, which may underlie platelet hyperactivity. Platelet ATP and ADP levels, thiobarbituric acid-reactive species synthesis, and aggregation of platelets from p...
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We have previously described a fluorimetric method to measure ADP-ATP exchange rates in mitochondria of permeabilized cells where phosphorylases, kinases, ion pumps exhibiting substantial ATP hydrolase activity and other competing reactions interconverting adenine nucleotides are present. This was achieved by recording changes in free extramitochondrial [Mg] reported by the Mg-sensitive fluores...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 1995
ISSN: 0005-2736
DOI: 10.1016/0005-2736(95)00038-5